Description: Angiogenesis : From Basic Science and Clinical Aspects, Hardcover by Ferrara, Napoleone (EDT), ISBN 0849328446, ISBN-13 9780849328442, Brand New, Free shipping in the US While angiogenesis, the process in which new blood vessels grow from pre-existing vessels is a normal part of growth and development, it also plays a key role in the transition of tumors from dormant to malignant states, prompting researchers to explore the use of anti-angiogenesis agents in therapeutic applications. In this work, Ferrara (Genentech, Inc.) presents examples of recent work in the field, looking at advances in the basic science and in clinical studies with inhibitors of angiogenesis. Particular topics covered by the 13 chapters include pathophysiology and clinical implications of vascular endothelial growth factor (VEGF-a signaling protein), signal transduction of VEGF receptors toward angiogenesis, growth factors and lymphangiogenesis, neural guidance molecules in vascular development, non-angiogenic functions of VEGF, contribution of pro-angiogenic hematopoietic cells to vascularization of tumor and ischemic tissues, antiangiogenic drugs as broadly effective chemosensitizing agents, ocular neovascularization, and therapeutic angiogenesis for cardiovascular disease. Annotation ©2006 Book News, Inc., Portland, OR ()
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Book Title: Angiogenesis : From Basic Science and Clinical Aspects
Item Length: 9.5in
Item Height: 0.8in
Item Width: 6.4in
Author: Napoleone FERRARA
Publication Name: Angiogenesis : from Basic Science to Clinical Applications
Format: Hardcover
Language: English
Publisher: CRC Press LLC
Publication Year: 2006
Type: Textbook
Item Weight: 20.2 Oz
Number of Pages: 280 Pages
