Genentech The Beginnings of Biotech by Sally Smith Hughes (English) Paperback Bo

Description: Genentech The Beginnings of Biotech by Sally Smith Hughes In the fall of 1980, Genentech, Inc, a little-known California genetic engineering company, became the overnight darling of Wall Street, raising $38 million in its initial public stock offering. This title provides portraits of the people significant to Genentechs science and business, and focuses on how personality affects the growth of science. FORMAT Paperback LANGUAGE English CONDITION Brand New Publisher Description In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentechs improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentechs science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentechs founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, Genentech tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it. Author Biography Sally Smith Hughes is a historian of science at the Bancroft Library at the University of California, Berkeley. She is the author of The Virus: A History of the Concept and the creator of an extensive collection of in-depth oral histories on bioscience, biomedicine, and biotechnology. Table of Contents Prologue Acknowledgments 1 / Inventing Recombinant DNA Technology Two Scientists on Converging Paths The Collaboration Patenting and Politics Steps toward Commercialization 2 / Creating Genentech Bob Swanson Founding Genentech Legal and Political Obstacles A Full Business Plan 3 / Proving the Technology A Portentous Experiment Switching Targets Negotiating Research Agreements Making Somatostatin Wider Issues 4 / Human Insulin: Genentech Makes its Mark Seeking Corporate Contracts Procuring a Facility and Staff Genentechs Human Insulin Project The Eli Lilly Contract Publicity and Expansion 5 / Human Growth Hormone: Shaping a Commercial Future Competing for Human Growth Hormone Moving toward Corporate Integration Scaling Up Insulin and Growth Hormone Corporate Expansion An Emerging Culture 6 / Wall Street Debut Biomania Exit Strategies Interferon: The New Wonder Drug? Run-up to an Initial Public Offering Legal Impediments The IPO Epilogue Notes Bibliography Oral History Bibliography Index Review "Sally Smith Hughes has crafted an engaging historical account of Genentech from its beginnings as a small laboratory at the University of California, San Francisco to the 2009 merger with Roche for $47 billion.... Her account will appeal to a broad audience and is a must read for scholars interested in the history of biotechnology. Highly recommended." (Choice)" Review Quote "The author skillfully reveals the practical, day-to-day, hands-on roles played by venture capitalists focused on fiscal gain and scientists focused on scientific breakthroughs. . . . [A] fascinating read." Details ISBN022604551X Author Sally Smith Hughes Short Title GENENTECH Language English ISBN-10 022604551X ISBN-13 9780226045511 Media Book Format Paperback Year 2013 Imprint University of Chicago Press Subtitle The Beginnings of Biotech Place of Publication Chicago, IL Country of Publication United States DEWEY 338.476606509794 Illustrations 19 halftones Publication Date 2013-04-08 NZ Release Date 2013-04-08 US Release Date 2013-04-08 UK Release Date 2013-04-08 Pages 232 Publisher The University of Chicago Press Series Synthesis (CHUP) Audience Professional & Vocational AU Release Date 2013-04-07 We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:130701074;

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